WebMar 9, 2024 · Cardiovascular disease is the leading cause of mortality globally with at least 26 million people worldwide living with heart failure (HF). Metabolism has been an active area of investigation in the setting of HF since the heart demands a high rate of ATP turnover to maintain homeostasis. With the advent of -omic technologies, specifically … WebMar 14, 2008 · Amino acids and acyl-carnitine species were measured using flow injection tandem mass spectrometry and sample preparation methods described previously ,. Briefly, samples were equilibrated with a cocktail of internal standards, de-proteinated by precipitation with methanol, aliquoted supernatants were dried, and then esterified with …
(PDF) Metabolomic Profile in Venous Thromboembolism (VTE)
WebDec 2, 2024 · Carnitine-fatty acid and amino acid metabolic pathways exhibit progressive dysregulation from normoglycemia to T2D and further to diabetic nephropathy. Prospective studies in both men and women... WebApr 16, 2012 · To determine if caloric restriction (CR) would cause changes in plasma metabolic intermediates in response to a mixed meal, suggestive of changes in the capacity to adapt fuel oxidation to fuel availability or metabolic flexibility, and to determine how any such changes relate to insulin sensitivity (S(I)).Forty-six volunteers were randomized to a … basf japan 住所
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WebMar 25, 2024 · Acylcarnitine and/or acylcarnitine ratio in patients with carnitine acylcarnitine translocase and carnitine palmitoyl transferase deficiency showed an abnormal profile regardless of the metabolic status of patients. The acylcarnitine was derived from the analysis of dried blood spot using multiple reaction monitoring (MRM) which was … WebNational Center for Biotechnology Information WebTetradecanoyl (C14:0) and palmitoleoyl (C16:1) carnitines were significantly less abundant in HFD dam serum and HFD-L pup serum than in CON and CON-L animals (P < 0.05, Table 4). Moreover, maternal HFD exposure in pups significantly decreased the relative abundance of palmitoyl (C16:0), arachidyl (C20:0), and cervonyl (C22:6) carnitines. basf japan 売上